Activation of Subthalamic Nucleus Stop Circuit Disrupts Cognitive Performance
نویسندگان
چکیده
منابع مشابه
Stop-signal reaction-time task performance: role of prefrontal cortex and subthalamic nucleus.
The stop-signal reaction-time (SSRT) task measures inhibition of a response that has already been initiated, that is, the ability to stop. Human subjects classified as "impulsive," for example, those with attention deficit and hyperactivity disorder, are slower to respond to the stop signal. Although functional and structural imaging studies in humans have implicated frontal and basal ganglia c...
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The subthalamic nucleus (STN) is the most common target for the treatment of Parkinson’s disease (PD) with deep brain stimulation (DBS). DBS of the globus pallidus internus (GPi) is also effective in the treatment of PD. The output fibers of the GPi that form the lenticular fasciculus pass in close proximity to STN DBS electrodes. In turn, both STN projection neurons and GPi fibers of passage r...
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Introduction: Parkinson’s disease is one of the most disabling diseases which by electrode implantation and stimulation of subthalamic nucleus (STN), much progress has been made in the treatment of drug resistant patient. This new method of neurosurgery may have some neuropsychological side effects on the patients. The main aim of this study is to evaluate the effects of this kind of treatment ...
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ژورنال
عنوان ژورنال: eneuro
سال: 2020
ISSN: 2373-2822
DOI: 10.1523/eneuro.0159-20.2020